The Cystic Fibrosis Foundation’s key metric for measuring success is our drug development pipeline. Our mission is to develop new therapies and a cure for cystic fibrosis. To achieve this goal, we need to have a broad range of potential drugs in development that attack the disease from every angle because many drugs may never make it to market.
CF is a complex disease and therapies must target problems in the airways and the digestive system. In the CF drug development pipeline, there also are promising new therapies designed to fix the cause of CF — a faulty gene and/or its faulty protein product.
The CF Foundation seeks to increase its odds of success by keeping this pipeline “stocked,” closely evaluating and tracking the progress of each therapy as it moves through development and — at the same time — pursuing new opportunities for future drugs to be developed.
Below is a "snapshot" of those potential CF therapies that are currently in development as of January 10, 2011.
Let me tell you quickly what some of this below means before you look at it. Gene therapy is what they believe will cure CF. There is a cure for CF. Doctors and scientists have found a way to correct the faulty gene. They have not yet found a way to get it into patients and stick. CFTR Modulation essentially corrects the basic defect of CF, allowing chloride and sodium to move properly in and out of cells lining the lungs and other organs. In 2012, some of these drugs will become available to patients. In 2012, if enough support is raised for the CF Foundation to continue their research and clinical trials, Drew may be able to receive these medications and be symptom free. He will not be cured, but he will be better. This is how close we are. You can read more about this on the CFF website, or by clicking here.
Stay tuned for the rollout of our Great Strides campaign. I'm thinking the beginning of February so that we have 3 good months of fundraising. And just so you know, if you ask me how you can help, I will give you a LIST of ideas :)